A herbal product has promising results in experimental endometriosis
Neroli oil (bitter orange) is a nontoxic volatile substance from the flowers of Citrus aurantium that belongs to the Rutaceae family. This oil has notable anti-inflammatory effects besides potent antioxidant activity with 100% singlet oxygen scavenging activity. Contemporary pathophysiological views…
Key Points Lay SummaryLow-Dose Aspirin as a Potential Treatment for Endometriosis-Related Infertility
Treatment with low-dose aspirin could downregulate progesterone resistance and increase the expression of leukemia inhibitory factor (LIF) during the implantation window, according to a study that used a rat model of endometriosis. This, in turn, could improve endometrial receptivity and…
Key Points Lay SummaryNew Rat Model of Endometriosis Could Help Researchers Develop New Treatments for the Condition
Researchers in Belgium developed a new rat model of endometriosis. The animals showed signs of ongoing pain meaning that the model could provide a tool for researchers to develop potential new ways to treat the different symptoms of the condition…
Key Points Lay SummaryCabergoline or Progesterone not Effective in Rat Model of Endometriosis
Oral treatment with cabergoline or micronized progesterone for four weeks is not effective in the regression of endometriotic implants in a rat model of the disease. This is according to a study published in the "Journal of Investigative Surgery". Cabergoline…
Key Points Lay SummaryEndometriosis signaling: the role of IL-34
An increasing number of studies have suggested that the pathogenesis of endometriosis is mediated by cytokines, such as interleukin (IL)−17, which promoted the formation and progression of endometriosis by up-regulating angiogenesis and pro-inflammatory cytokines secretion. IL-34 is a newly described…
Key Points Lay SummaryKidney Hormone Potential Treatment for Endometriosis?
Erythropoietin, a hormone produced by the kidneys to promote the production of red blood cells could be a promising candidate for the treatment of endometriosis. This is according to a study published in the Journal Of The Turkish-German Gynecological Association by…
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